Genetic differences help explain cigarette addiction.

Two new studies of smokers have yielded new insight into a gene linked to cigarette addiction. The findings could lead to more personalised, and ultimately more effective, treatments that help people to quit smoking.

Both groups examined the numerous forms of a gene called CYP2A6, which codes for an enzyme that acts mostly in the liver and regulates nicotine metabolism in the body. Previous research revealed that people with an ineffective form of the gene are less likely to become addicted to smoking.

Experts think that nicotine levels remain elevated for longer in these individuals, delaying the craving for the next cigarette. Nicotine is the primary chemical responsible for smoking addiction.

[thanks, Fark, bock bock!]